Well this should actually never happen to a 2UZ-FE V8 engine! Aren't they known for reliability?

Started getting engine fail signal, not steady but blinking yellow sign, reading as "misfire cylinder 3". I was on a 400mile trip in the middle of nowhere and could not stop. 50 miles later there is a screeching sound coming from the engine, obviously something wrong with cylinder 3. I can see without disassembling the engine that on cylinder 3 there are explosions lifting the assembly with the spark plug slightly. Damn! Still got 100 miles to go!

Engine runs rough, clearly there is an issue with power, although the remaining 7 cylinders still produce enough power for the ride. Once I reach home the screeching sound is so loud that I am scared I might have blown the entire engine!

Was searching all over the net to find similar symptoms but could not find anything with these symptoms. Belt was changed, oil also, just two hours before the problem appeared the engine was running smooth and powerful and gave no indication of a mechanical problem.

Shoot, this was for the last 6 years my best ride ever! The T4R was the most reliable and comfortable I ever owned! Don't wanna loose it!

Any ideas? My guess: broken valves? Stuck ventil? Will need a mechanic for that, my skills are not sufficient for these type of problems.