The difference between E10 and E15 is negligible. Any 3rd gen, even pre-2001 should run E15 with no issue. Ethanol isn't any more corrosive to fuel systems than gasoline. The only caveat is if it's mixed with water. So just don't put water in your fuel tank and you'll be good.

There are old arguments that say it will readily absorb moisture from the air, but this is very silly since the fuel systems are sealed.
Ethanol is a good solvent, so if anything it may clean the fuel injectors which will improve performance.
The energy density of ethanol is lower than gasoline, so you may notice a decrease in fuel economy. This is normal. Depending on the price of gas, it may be a wash in terms of actual $$ per mile for fuel consumed.
I've been running E85 for a while (supercharged, larger injectors, etc) and it is considerably cheaper than gasoline even after accounting for the decrease in fuel economy. The price of ethanol has remained relatively stable while the price of gasoline has gone up significantly.
The other bonus of ethanol is the high octane rating (average 105 octane), which is especially nice for supercharged applications.