that the a car like the Lexus RX330 or RX350 fuel cost is same or worse than the V6 4Runner.
Compare Side-by-Side
Given that the 4runner is heavier, wider tires, truck based SUV, boxy shape, etc. It would be cost more on fuel than a Lexus RX. I know partly the reason is because the Lexus uses premium fuel but had no idea it cost more to operate as far as fuel goes.