I just installed the Old Man Emu 2" lift on my 2007 4Runner. I have the stock wheels and a set of 2007 FJ Cruiser 17" wheels. The FJ wheel offset is a bit more than the 4Runner wheel offset. As a result, they give my 4Runner what appears to be a slightly wider stance. I used the FJ wheels with my snow tires pre-lift installation and they worked fine with no issues using stock sized snow tires - 265/65R17.
I will soon be installing some Falken 265/70R17 tires on the 4Runner wheels and selling the FJ wheels.
A great resource for questions is Slee Offroad in Golden, CO. They really know their stuff when it comes to 4Runners.
Sleeoffroad.com - Toyota SUV Off-Road Outfitters