Migraine Tied to Increased Risks for Myocardial Infarction, Stroke
By Amy Orciari Herman

Edited by Susan Sadoughi, MD, and Richard Saitz, MD, MPH, FACP, DFASAM

Migraine is associated with increased risks for numerous cardiovascular outcomes, a study in The BMJ finds.

Using Danish health and population registries, researchers matched 51,000 patients with migraine diagnoses to 510,000 migraine-free individuals (median age, 35). During 19 years' follow-up, cardiovascular events were significantly more common in the migraine cohort. Here are the incidences per 1000 population in people with migraine versus controls:

Myocardial infarction: 25 vs. 17
Ischemic stroke: 45 vs. 25
Hemorrhagic stroke: 11 vs. 6
Venous thromboembolism: 27 vs. 18
Atrial fibrillation or flutter: 47 vs. 34
Associations were stronger for migraine with than without aura.

The researchers write, "Migraine should be considered a potent and persistent risk factor for most cardiovascular diseases in both men and women."

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