I just put on a set of 305/70/16. At the same time I installed my lift...Toytech ultimate lift. I have the front set at 2 1/2 inches and also installed 1.25 wheel spacers. I have no body lift. After everything was installed, I ended up having to trim a small corner of the front fender flare (I have the big limited flares). I then changed the "bolt head" hardware that mounts the flares, to "flat" head hardware. I ran like that for a couple of days and all was well. But the tires were very close to the back of the wheel well. Therefore, I went a head and did the pinch well mod.
Since then...I haven't had any tire rub. But still haven't been off road yet. I love the wider tire stance, so if it does rub...I'll do a 1" body lift.