I went from the stock 20s to a flat black 6 spoke aggressive looking Fuel 18 (about $1,000) with 275/65/18/9 BF Goodrich All-Terrain TAs (another $1,000) and a Spidertrax 1.25" spacer ($225 for 4) and I'm really happy with everything.

That said, there was rubbing even with a 2" level/lift kit ($750) so I had to have the shop shave away some BS underneath and remove my front mudflaps. ($200).

For about 3 grand it totally changed my truck from a soccer-mom vehicle to a beast starter-kit. Adding the roof accessories, the blackout kit for the logos, and the ladder got me close to where I want to be and there's no real appreciable difference in the sound or ride, but I no longer fear potholes.