I've had experience with both, an 05 Ex (2wd), and an 09 T4R (4wd). Understanding that difference, the Ex was a great highway crusier, had lots of room, was quiet and comfortable. In 30,000 miles, I replaced the front brakes twice, but had no other problems, and I probably would have been happy keeping it. Rumors abounded about the differential and transmission, but I didn't experience problems with either one. Mileage was okay considering the size and power of the vehicle.
So why did I trade it? I made the mistake(?) of driving an 08 T4R from Sacramento to San Jose. In that 130 mile trip, I experienced more driving enjoyment than I ever had in the Ex. It is just more of a "drivers" vehicle. Better accelleration, road feel, control. After that trip, I wanted a T4R. It's not to say that a 4wd Ex would have been the same, but I doubt it. In the few times I have driven a 4wd Ex, I have not been impressed. (I work for one of the major car rental companies.)
One other thing. In looking at KBB values, just for fun--my 09 T4R is worth much more as a percentage of new vehicle cost, than a similiarly equiped 09 Ex.
Just my opinion.
Bill W