My 89 1st gen runner with the 3.0 has 315K on him. At 250k (about 7 years ago) the block was swapped out for a one that Warn rebuilt and had drilled out the water channels a bit to avoid overheating and head gasket issues. The tranny was overhauled at the same time and this thing runs like a top.
My runner up was my beloved 96 Tacoma with the 2.4 liter that blew the head gasket and/or cracked the head at 249,550 miles. This was my fault, as I promised that I was going to drive it to 250k and putting it up for sale, the head went two days later.
I have had somewhere around 13 cars, suvs and trucks in my 20 years of marriage and the 6 best were the Toyotas for sure, oh and the Lexus.