It's a matter of making sure everything is level. I know you can chuck the DOM in a lathe, and use the center point on the head stock to hold the tap. This would hold the tap perfectly level with the DOM, and would give you a straight hole. My problem is that the center bore on my lathe is not large enough, and I don' feel like shelling out money for a larger 3 piece chuck.
Trying to manually turn a 1-14 tap while trying to keep is completely level is pretty tough.