170* is not that much cooler, but it might make a difference. In theory, the thermostat sets the minimum temperature, which is the temp the engineers determined is
required for best performance, mileage, wear, etc. The electronics (ECM) are programmed for things to work best at that temp. Putting in a cooler thermostat won't keep the car from overheating or running hot (contrary to how it might seem); but it can keep it from reaching optimum operating temperature, costing mileage, wear, etc. It's probably not so much the fuel atomization - would have more impact on a carbureted engine - but that the computer is assuming that normal operating temp is around 200 and will adjust things based on that. But, the ECM will compensate for the effects of the lower temp on the fuel mixture using feedback from the O2 sensors, so it shouldn't affect mileage much, if any. I would be more concerned about wear on the engine components.
In high-performance applications (like the 65 Mustang I built -
http://www.cardomain.com/ride/3838887/1965-ford-mustang/) you usually run cooler thermostats to ward off detonation when using superchargers or turbochargers, and there is a small power gain possible, even with normally-aspirated engines (when you are looking for every last HP). But the downside is usually increased engine wear (in the long term), and sometimes poorer mileage.
If you are concerned about the heat in Belize, a cooler thermostat won't help keep it cool. I don't think these 4Runners have problems with overheating. I have had mine crawling through the woods on 95 deg days in low range with no change in temp - it stays at 200* (+/- 2* or 3*) in any weather. Unless you are doing serious rock crawling in Death Valley, I think the factory cooling system is more than adequate. But, do make sure that your clutch fan is working, your radiator is clean, and your fan shroud is intact and in place.