Seems like a long shot...but could this mileage be linked to the top of the 4runner? I dont know if you keep it off or have recently removed it. Might change the areo dynamic drag on the vehicle? Just a thought.
And just for follow up...Octane is added to fuel to prevent 'early combustion' from taking place. The pressure and heat in the cylinder can combust the air/fuel mixture before the actual 'spark' so you get early combustion (knock). So octane helps the fuel resist pre-combustion. I think it mis-advertised as a power adder, but thats not it's purpose.
If your vehicle has a compression ratio of greater than or equal to 10:1 I think its typically recommended. The more cylinder volume, the more pressure and risk of pre-combustion. For example my honda 07 civic runs 87, but my brothers 08 civic si ran premium. Larger compression ratio.
Maybe consider anything that could add rolling resistance to the truck...wheel bearings, or any bearings in the mechanical driveline really.
Also, you need 14.7 parts of air for every 1 part of fuel. So you could be wasting fuel by not having enough air to burn it (running rich). Any possibility air is being restricted? Vacuum lines etc?? Clogged air filter?
Good luck!