This was done after a family vacation around the US. We drove from Oklahoma to the Dakotas, Wyoming, Montana, Colorado, Utah, Arizona, New Mexico, Texas, etc. It was a lot of highway miles, but I drove it pretty hard. 80 - 85 through the mountains of Utah was pretty common. We also drove over the Bear Tooths a few times which is around 12000 ft if I remember right. We were loaded, but were not towing.
Edit: Meant to say, I've been using nothing but Toyota brand oil and filters for the last 30,000 which is when I bought the truck.