Yup, get a good VOM and learn how to use it.
My guess is you have a short to ground, which may have zapped your in-line fuse (near the battery), the fuse(s) on your amp, or the circuit that turns your amp on (internal).
Once you have your VOM, check for 12V+ across the + and - terminals on your amp. If that checks out, you have sufficient voltage and an acceptable ground thus far. Then it comes down to whether the amp is getting the turn-on signal from your head unit.