If you haven't already, run the carfax, and get the vin and register on Toyota Owners Website to get as much history on the vehicle as you can.
07 with 22k miles is super low. 5500 miles/year? thats only 456 miles a month being driven. If it was a grandpas car, maybe legit. Otherwise, it could be suspect.
Not sure how mechanically inclined you are, but bring a flashlight and inspect everything, and take your time checking it out, especially if you are going to drive that far to see it.
Heres a short list of things Ive done with my current and previous vehicles. You dont want the long list and my random ADHD wont let me type all of it :jump:
1. Pull the oil dipstick and see how dirty the oil looks
2. If its automatic and there is a transmission dipstick, pull it and look at the fluid, it should be fairly light in color with only 22k on it.
3. Look at the nuts and bolt ends of major engine/suspension parts, do they look like they have been wrenched on?
4. Drive it like you stole it with the radio off and windows down, any strange noises/vehicle behavior usually come out when driven hard.
5. Look at the brake fluid resovoir, if the fluid is light colored, you should be ok.
6. Check rotors for scoring and uneven wear.
7. Check the radiator for any dents/dings to cooling fins. The sides should have no dents/dings. This can be an indicator of front end collision.
WARNING: I also suffer from random OCD and these things most people may consider as excessive, but if I'm spending the money, I can be as critical as I want.
Good luck!