Yes, running into a moose at night with your vehicle is something we all want to avoid, especially if you're in a car.
Moose have long, thin legs, and if you hit one head-on in a car at speed, you'll break all the legs and the hefty body will slide neatly over your hood, and propel right through your windshield.
Don't expect airbags to save your head and upper body from that.
Also, moose are incredibly stupid critters. I've been on a hunting trip where there were 3 moose standing together, shoulder to shoulder. My hunting partner, who is a much better shot than I, shot the big bull. The bull immediately fell down dead, but the other two just stood there, munching on tundra plants.
We eventually had to chase away the two survivors before we could dress out the victim.
I think that in a 4Runner, you'd be high enough to survive a collision with an adult bull moose, but your engine and front end would be modified to the junkyard.
JP