I would think that porting & polishing the heads and lower intake manifold would make a bigger difference for less money, while not requiring a full rebuild. I guess if you were having the engine rebuilt, then why not go for it, and check into some cams, too. Also, I wouldn't be surprised if I learned that there was limited room/material thickness available to bore out a 5VZ block.
I'd be looking at the options if I were doing a re-build, but for someone starting out with a healthy motor, the answer is simple...
$$$$ : benefit ratio.
BTW, edit:
No. Plenty of us are "properly" supercharged, and still running stock internals.