i recently had a problem with my 2001 4runner it had a cylinder 6 misfire so at about 50mph the car would start to stutter which felt like the transmission was slipping but i brought it to a garage and it turned out to be the coils so he replaced them and it fixed the problem for a while, now a couple weeks ago i started my 4runner in the cold and before it was fully heated up it sounded like it wanted to stall out and now at around 50mph its starting to misfire again (the coils where replaced last year). im not sure what the problem is anymore.