I have the Eclipse AVN2454 works great as a navigation unit and dvd player. I was going to install it in the 4runner but ended up putting it in my VW GTI. It is a 2 din unit. It just won't work with the rear seat audio and cordless headphones for my kids. If you have the steering wheel controls it will work with the pac switch.
You could also check out the Eclipse AVX2494 which is also a DVD player with 20 gig harddrive less the nav system.