So, you have ZERO OEM keys? Not much you can do there. If you have valet key, a mobile locksmith is your best bet. Have them come out, flash the ECU (assuming the truck has the transponder key with the immobilizer computer), and cut you new transponder keys. It won't be cheap. $450 is probably about right, unfortunately.
When I went through this, I had an OEM transponder key, but I changed my ECU (the old one was fried). Mobile locksmith came to my house, took my key and my ECU and made them talk nice to each other. Also had him cut me a new transponder key. That was $220, I believe. The key blanks are expensive on their own.