'08 Highlander
I test drove an '08 Highlander just before I bought my t4r. It was competent in most respects but had little in the way of any kind of personality. Not something any self respecting guy could fall in love with. That said, it may be just fine for your wife. One nice feature is the fact that you can get a back up camera without the need to go with the full nav system. God knows I am trying to find a way to retrofit my wife's '07 Rav4 with a backup camera without breaking the bank.
By the way, if your wife doesn't need the slightly larger size of the Highlander, have you tried a V6 Rav4? They are a hoot to drive and very comfortable and those who own them seem to wear a permanent smile on their faces. You can probably get a fully loaded one and save $$ over the Highlander. You can even retrofit it with the full nav, if your heart so desires.