Another +1 for the 1UP racks, and +2 for the RakAttach swing-arm (
http://rakattach.com/ - also sold directly through 1UP). This is my setup for long trips where I'm hauling myself plus one or two other bikes and gear. A 4th bike is an option for the rack, though that's getting a little out of my comfort zone for practicality, stability and effective vehicle length. This is the heavy duty 2-bike base rack, plus a single heavy duty add-on. The Super Duty rack is the same as this, but has an extra reinforcing piece that goes between the trays to allow carrying heavier bikes >50lbs.
The whole setup feels really solid on the road. The RakAttach has a locking pin as well as a compression clamp and plastic bushings, so there is no rattle or shake. It only takes 15 seconds to unpin it, unclamp it, and swing it out. A bit longer if you have the bikes cable locked to the safety loops on the receiver of the truck and you don't have enough slack in the cable. FYI this is a size LARGE RakAttach. They come in 3 sizes, which essentially determines how far away the bikes will swing from the vehicle.
I have some ideas about fabricating something that attaches to the swing-out. Maybe holding a small 5lb propane bottle and providing a small fold down surface for setting up a camp stove and cooking when I do destination rides with camping involved.
For my everyday rides where it's just me and my gear, I favor my solution that I built into my custom drawer system. Keeps the bike more protected and it's a bit more stealthy.