Congrats on passing 200k!
My 4th gen is now around 205k miles. In the last 10k miles I've replaced;
Front wheel bearings- front left was getting loud on turns, no play in wheels
F & R brake rotors and pads- had close to 100k miles on previous brakes and pads were getting thin and some slight pulsing
Alternator, idler pulleys, tensioner, belt- Went to leave for work one sunny day and the alternator literally locked up in my driveway and smoked the belt. Figured I'd change out the idlers and tensioner while I was in there. The best place to break down is at home with another vehicle available to drive.
Front coilovers- the 6112 billies started leaking pretty bad and they didn't feel right, had about 50k miles on them, Dobinsons went in their place.
Front lower A-arms/ balljoints- The bushings were shot and I figured I might as well do the balljoints while I was in there. Premium Moog arms and BJs installed. I'm not confident they will last long, made in chyna.
Alarm and remote start- the 14 year old Avitel RS was getting very hit and miss when it would lock, unlock, start. Tried a few known "fixes" without success so a new, cheap Crimestopper unit installed.
Brake master cylinder and booster unit- by far the most expensive and probably the most important fix on this 4runner. Never fully lost the brakes but the booster motor was screaming every 2-3 seconds and the pedal feel was inconsistent. Nearly $1200 but an easy install and bleed. Brakes feel as good as new now.
Rear hatch exterior button pad- unfortunately, this 4th gen now sits outside in the hot NM sun most days and the button just started melting one day. I only replaced the pad, not the entire button.
So, quite a few repairs over the course of roughly 10k miles but not all were the 4runners fault or were even OEM parts. There's quite a few off-road miles on this 4th gen over the last 8 years so not all of this is a surprise at all. Still cheaper than a new vehicle payment and I still enjoy driving this thing after all these years.
Every vehicle is different- environment, maintenance, use, etc. all plays a part in when parts start to fail. Some go over 300k miles with no issues at all, some are replacing parts before 100k miles.