P0300 P0306 Misfire fixed - fuel injector '99 4Runner

Ok, before you go as far as swapping the ECU -

Swap the injectors/plugs on the problem cylinders with 2 good ones. Meaning swap 1 & 5 with say 2 & 4. See if the misfire follows. If it does, you got bad components. If not, the problem is elsewhere.
 
Like Jahmiroquai suggested, swap with 2 and 4 and see what pops.

When I was throwing parts at my cylinder 1 misfire, I acquired a used ECU to rule that out. Same code popped. Now, I have an extra ECU. Let me know if you’re interested; super easy swap that takes 30 min.
 

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