I don't know...I think people are overthinking this. Unichip is obviously a reputible company and they sell alot of product. Somehow I don't think they'd be in business if they went around burning peoples engines up. Like Casper and other people who have tuned cars before have said; its a relatively safe product and they've had success with it before in the past with no problems and I believe it. I just think people are skeptical because no one here has tried one on the 4Runner, which is what I'm going to do, and good or bad I will report my results (maybe have a dyno run or two also, there is an AWD dyno about 10 minutes from my house).
Even with the risk of leaning out the mix to the point it would cause engine damage, they (Unichip or whoever programs it) would have to be pretty wrong on air/fuel volumes and ratios to cause damage; not exactly their advertised claim of increasing horsepower by making "superfine adjustments to the air/fuel ratio for optimum power" Now, I'm not 100% sure here, but isn't there a little window between the stoichiometric air/fuel ratio and the air/fuel ratio that will burn your engine up? Just like there is a little window on the rich side? Its not like if the mix gets .0001% lean your engine will burn, right? So, my point is they obviously tuned this thing on a test vehicle to get the base map, so it may even be a touch rich to start with. Then small adjustments are made to optimize the mix for intake and/or exhaust, none of which I would think are drastic enough to cause engine damage. During all of my research, I haven't come across any stories or tales of a Unichip destroying someone's engine. Just to be safe, however, I will make a trip to the dyno w/ O2 sensor just to be sure, then I will report the results for all to see.