4 channels, your front speakers are actually split into 4 speakers but they're only 2 channels, if you get a set of matched components they will have tweeters and woofers that can be installed seperate. The rear doors have just 1 speaker in each, but most components allow you to mount the tweeter directly to the woofer. I will be installing my speakers soon and will have a detailed write up. But I'm only using a 4 channel amp with front and rear component speakers.
If you're just replacing the radio and not adding an amp, any head unit will come with 4 channels of speaker outputs. And if you're using the stock wiring, the front channels are already split.