From all the reading I've been doing on automotive forums for the past couple years I can guarantee you that all those new electronics will be problematic. Go read the Tundra forums to hear about all the problems with the new Tundra with the twin-turbo V6.
Depends. It's been long enough now that I think many people forget that electronics dramatically improved reliability in the 80s and 90s.
As far as "all the problems with the new Tundra", the thing eeeverybody quotes is the one whole first batch of junk turbos from a junk supplier who got canned. I haven't heard any significant reliability problems from Tundras after the first few months of production. That engine is in the LX, Sequoia, and now other things, and it does not appear to be ruining lives.
First year teething problems happen on new platforms or powertrains sometimes. Some may not know or remember that the "impossibly reliable" 4.0L 1GR V6 had some issues including popping headgaskets on the first couple model years.
If you're pathologic about reliability, might as well stick with a 5th gen since the tech is 20 years old. I would consider a GX460 a slight downgrade in the reliability department, I have heard of plenty of those full-time transfer cases failing.
Toyota is not an American brand out to build trucks that puke at 80,000 miles, so I really wouldn't be worried about ANY new Toyota truck product. Anything can technically break, but it's all about likelihood, and Toyotas at large are unlikely to ruin your life or strand you.
Forums have a habit of amplifying a small amount of voices of people who have had problems. Read enough into forums and you'll think every vehicle is a ticking time bomb for everyone. The reality is that for every Toyota owner posting a problem on a forum, there's 50 owners who don't have problems, and therefore don't have anything to post. Ordinary people do not search for a forum and create an account just to post that everything is fine, all good in the neighborhood.