I would get the cylinder 2 misfire fixed first. Check the spark plug first or just replace all the plugs if you have more than 30k miles on standard plugs, 60k for platinum, or 90k for iridium. If the problem persists then you will need to swap coil packs and wires to rule out ignition issues. The P0141 can be the rear O2 sensor which typically goes bad around 100k -150k miles anyway.