Finally Good news: Coffee
- Thread starter Thai
- Start date
Thai
Elite Member
To coffee lovers:
Does Coffee Promote Atrial Ectopy?
Molly S. Brett, MD, reviewing Marcus GM et al. N Engl J Med 2023 Mar 23
Caffeinated coffee was not associated with premature atrial contractions in this small, randomized trial.
Although many people believe that caffeinated coffee can cause cardiac ectopy, prior studies (mostly observational) have cast doubt on this alleged relation. In this randomized case-crossover study, 100 healthy adults (mean age, 39) without atrial fibrillation or heart failure wore continuous-recording electrocardiogram (ECG) patches and wrist accelerometers for 14 days. During this time, they were instructed randomly by text message to consume caffeinated coffee or avoid all caffeine during 2-day periods, resulting in 7 coffee-drinking periods and 7 no-caffeine periods. Participants pressed a button on their ECG patch when each coffee drink was consumed and filled out daily surveys about consumption.
At baseline, most participants consumed <1 cup of coffee daily. During the study, when participants were assigned to drink coffee, most drank 2 to 3 cups daily. The number of daily premature atrial contractions (PACs) was nearly identical on days with or without caffeinated coffee consumption (mean, 58 vs. 53 PACs daily). In exploratory analyses, more premature ventricular contractions (PVCs) occurred on coffee-drinking days (mean, 154 vs. 102 daily). Participants had higher step counts (≈1000 more steps) and less sleep (≈30 minutes less) on days they consumed coffee.
COMMENT
This trial provides further evidence that moderate coffee drinking is unlikely to cause atrial ectopy in healthy patients. The clinical significance of the small increase in daily PVCs observed on coffee-drinking days is uncertain. For healthy people, it's reasonable to leave decisions about coffee consumption to personal preference.
Does Coffee Promote Atrial Ectopy?
Molly S. Brett, MD, reviewing Marcus GM et al. N Engl J Med 2023 Mar 23
Caffeinated coffee was not associated with premature atrial contractions in this small, randomized trial.
Although many people believe that caffeinated coffee can cause cardiac ectopy, prior studies (mostly observational) have cast doubt on this alleged relation. In this randomized case-crossover study, 100 healthy adults (mean age, 39) without atrial fibrillation or heart failure wore continuous-recording electrocardiogram (ECG) patches and wrist accelerometers for 14 days. During this time, they were instructed randomly by text message to consume caffeinated coffee or avoid all caffeine during 2-day periods, resulting in 7 coffee-drinking periods and 7 no-caffeine periods. Participants pressed a button on their ECG patch when each coffee drink was consumed and filled out daily surveys about consumption.
At baseline, most participants consumed <1 cup of coffee daily. During the study, when participants were assigned to drink coffee, most drank 2 to 3 cups daily. The number of daily premature atrial contractions (PACs) was nearly identical on days with or without caffeinated coffee consumption (mean, 58 vs. 53 PACs daily). In exploratory analyses, more premature ventricular contractions (PVCs) occurred on coffee-drinking days (mean, 154 vs. 102 daily). Participants had higher step counts (≈1000 more steps) and less sleep (≈30 minutes less) on days they consumed coffee.
COMMENT
This trial provides further evidence that moderate coffee drinking is unlikely to cause atrial ectopy in healthy patients. The clinical significance of the small increase in daily PVCs observed on coffee-drinking days is uncertain. For healthy people, it's reasonable to leave decisions about coffee consumption to personal preference.
Thai
Elite Member
Coffee as a dietary strategy to prevent SARS-CoV-2 infection | Cell & Bioscience | Full Text
Both ground coffee and instant coffee were found to have benefits, as was decaffeinated coffee.
The coffee prevented entry of the SARS-CoV-2 infection by keeping the virus from entering host cells.
It did this by blocking the spike protein on SARS-COV-2 from binding to the enzyme ACE2, which is the primary receptor for the COVID-19 and is found in the lungs. It also reduced the activity of proteins and enzymes that are associated with severe COVID illness.
------------------------
Small study. But it adds to the MANY proven benefits of coffee (preferably caffeinated).
Both ground coffee and instant coffee were found to have benefits, as was decaffeinated coffee.
The coffee prevented entry of the SARS-CoV-2 infection by keeping the virus from entering host cells.
It did this by blocking the spike protein on SARS-COV-2 from binding to the enzyme ACE2, which is the primary receptor for the COVID-19 and is found in the lungs. It also reduced the activity of proteins and enzymes that are associated with severe COVID illness.
------------------------
Small study. But it adds to the MANY proven benefits of coffee (preferably caffeinated).
ramblin_wreck08
New member
This is really interesting, thanks for posting. As someone with an abnormal heart rhythm, including PAC/PVCs, I can confirm this has been my experience as well. Some of my most abnormal heart rhythms have occurred when I’m not regularly consuming coffee. There seems to be no direct correlation unless I’m loading up on caffeine and sugar at the same time (in unusually high quantities). Then things flare up a bit. Regular cardiovascular exercise and good sleep seem to help the most. Coffee is negligible relative to that.
Have really enjoyed reading through these. I’ll be sticking with my morning cup of black coffee.
Thai
Elite Member
New study...confirms coffee is great!
Does Coffee Raise Blood Pressure or Risk for Hypertension?
Sarah E. Post, MD, reviewing Trevano FQ et al. J Hypertens 2024 Jun
A cohort study shows no obvious effect on BP after 10 years of consumption.
Caffeine is a vasoactive compound that can raise blood pressure (BP) transiently, but data on the cardiovascular effects of habitual coffee drinking are mixed. In this prospective cohort study from Italy, researchers examined BP in 1400 participants who were stratified by self-reported daily coffee consumption: none, moderate (1–2 cups), or heavy (≥3 cups). Investigators collected office, home, and 24-hour ambulatory BP readings for each participant at baseline and after 10 years. Consumption categories for most participants did not change during follow-up.
The three groups were different somewhat at baseline: For example, heavy coffee consumers were younger, more likely to smoke, and less likely to be taking antihypertensive medications.
After adjustment for these confounders, the only significant finding was slightly lower mean office systolic BP in heavy consumers — compared with moderate consumers and nonconsumers — at baseline and 10-year follow-up; ambulatory and home readings were no different among groups at either time point. Measures of 24-hour BP variability and incidence of new hypertension were not different among groups.
COMMENT
These results suggest that regular coffee consumption does not lead to clinically meaningful differences in BP or incident hypertension. Patients can be reassured that a daily coffee habit is not likely to affect their BP.
Moreover, a recent large observational study suggested that coffee consumption is not associated with excess risk for cardiac arrhythmias.
Does Coffee Raise Blood Pressure or Risk for Hypertension?
Sarah E. Post, MD, reviewing Trevano FQ et al. J Hypertens 2024 Jun
A cohort study shows no obvious effect on BP after 10 years of consumption.
Caffeine is a vasoactive compound that can raise blood pressure (BP) transiently, but data on the cardiovascular effects of habitual coffee drinking are mixed. In this prospective cohort study from Italy, researchers examined BP in 1400 participants who were stratified by self-reported daily coffee consumption: none, moderate (1–2 cups), or heavy (≥3 cups). Investigators collected office, home, and 24-hour ambulatory BP readings for each participant at baseline and after 10 years. Consumption categories for most participants did not change during follow-up.
The three groups were different somewhat at baseline: For example, heavy coffee consumers were younger, more likely to smoke, and less likely to be taking antihypertensive medications.
After adjustment for these confounders, the only significant finding was slightly lower mean office systolic BP in heavy consumers — compared with moderate consumers and nonconsumers — at baseline and 10-year follow-up; ambulatory and home readings were no different among groups at either time point. Measures of 24-hour BP variability and incidence of new hypertension were not different among groups.
COMMENT
These results suggest that regular coffee consumption does not lead to clinically meaningful differences in BP or incident hypertension. Patients can be reassured that a daily coffee habit is not likely to affect their BP.
Moreover, a recent large observational study suggested that coffee consumption is not associated with excess risk for cardiac arrhythmias.
Thai
Elite Member
Habitual Coffee, Tea, and Caffeine Consumption, Circulating Metabolites, and the Risk of Cardiometabolic Multimorbidity | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic
Drinking several cups of caffeinated coffee and tea may protect against type 2 diabetes, coronary heart disease, and stroke, new research finds.
Researchers followed up with participants after about 12 years and found that drinking two-to-three cups of coffee, or up to three cups of tea, a day was the sweet spot for cardiometabolic health.
Specifically, coffee drinkers had the lowest risk—nearly 50% reduction in risk—while people who consumed 200 to 300 mg of caffeine from tea or a mix of both beverages were about 40% less likely to develop cardiometabolic disease.
The study discovered that even for people who consumed more than 400 mg of caffeine a day—just 4% of the study’s caffeine drinkers—the stimulant didn’t appear to have negative consequences for their cardiometabolic health.
Drinking several cups of caffeinated coffee and tea may protect against type 2 diabetes, coronary heart disease, and stroke, new research finds.
Researchers followed up with participants after about 12 years and found that drinking two-to-three cups of coffee, or up to three cups of tea, a day was the sweet spot for cardiometabolic health.
Specifically, coffee drinkers had the lowest risk—nearly 50% reduction in risk—while people who consumed 200 to 300 mg of caffeine from tea or a mix of both beverages were about 40% less likely to develop cardiometabolic disease.
The study discovered that even for people who consumed more than 400 mg of caffeine a day—just 4% of the study’s caffeine drinkers—the stimulant didn’t appear to have negative consequences for their cardiometabolic health.
Thai
Elite Member
Page restricted | ScienceDirect
Researchers found that drinking around three cups of coffee a day was associated with an extra 1.8 years of life, with regular cups also being associated with increased health span (time spent living free from serious disease).
The authors of the study noted that having coffee regularly appears to aid muscular, cardiovascular, mental, and immune system functions. And, it may be linked to a lower risk of developing some of the most frequent diseases affecting older adults, like cardiovascular and respiratory diseases, stroke, some cancers, diabetes, dementia, depression, or frailty.
Researchers found that drinking around three cups of coffee a day was associated with an extra 1.8 years of life, with regular cups also being associated with increased health span (time spent living free from serious disease).
The authors of the study noted that having coffee regularly appears to aid muscular, cardiovascular, mental, and immune system functions. And, it may be linked to a lower risk of developing some of the most frequent diseases affecting older adults, like cardiovascular and respiratory diseases, stroke, some cancers, diabetes, dementia, depression, or frailty.
Thai
Elite Member
Just a moment...
Drinking coffee in the morning may be more strongly associated with a lower risk of mortality than drinking coffee later in the day.
Dr Qi said further studies are needed to see if their findings could also be observed in other populations, adding: "We need clinical trials to test the potential impact of changing the time of day when people drink coffee."
"This study doesn't tell us why drinking coffee in the morning reduces the risk of death from cardiovascular disease," he explained.
"A possible explanation is that consuming coffee in the afternoon or evening may disrupt circadian rhythms [our bodies 24-hour cycle of physical, mental and behavioural changes] and levels of hormones such as melatonin.
"This, in turn, leads to changes in cardiovascular risk factors such as inflammation and blood pressure."
The researchers found that morning coffee drinkers were 16% less likely to have died compared to those who did not drink coffee, and 31% less likely to have died from heart disease.
They also saw no reduction in risk for all-day coffee drinkers compared to non-coffee drinkers.
The researchers said higher coffee intake amounts were "significantly" associated with a lower risk of death, but only among people who drank coffee in the morning compared with those who drank coffee all day.
Drinking coffee in the morning may be more strongly associated with a lower risk of mortality than drinking coffee later in the day.
Dr Qi said further studies are needed to see if their findings could also be observed in other populations, adding: "We need clinical trials to test the potential impact of changing the time of day when people drink coffee."
"This study doesn't tell us why drinking coffee in the morning reduces the risk of death from cardiovascular disease," he explained.
"A possible explanation is that consuming coffee in the afternoon or evening may disrupt circadian rhythms [our bodies 24-hour cycle of physical, mental and behavioural changes] and levels of hormones such as melatonin.
"This, in turn, leads to changes in cardiovascular risk factors such as inflammation and blood pressure."
The researchers found that morning coffee drinkers were 16% less likely to have died compared to those who did not drink coffee, and 31% less likely to have died from heart disease.
They also saw no reduction in risk for all-day coffee drinkers compared to non-coffee drinkers.
The researchers said higher coffee intake amounts were "significantly" associated with a lower risk of death, but only among people who drank coffee in the morning compared with those who drank coffee all day.
Last edited:
Thai
Elite Member
Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts | Nature Microbiology
Regular coffee drinking was linked to the growth of a specific gut bacterium called Lawsonibacter asaccharolyticus.
L. asaccharolyticus, which was first described in 2018, is a relatively understudied bacterium known to produce butyrate, a marker of adequate gut fermentation that indicates proper digestion and nutrient absorption.
The researchers discovered that coffee drinking correlated with an increase in several bacterial species, but the correlation with L. asaccharolyticus growth was by far the strongest, even with decaffeinated coffee.
Regular coffee drinking was linked to the growth of a specific gut bacterium called Lawsonibacter asaccharolyticus.
L. asaccharolyticus, which was first described in 2018, is a relatively understudied bacterium known to produce butyrate, a marker of adequate gut fermentation that indicates proper digestion and nutrient absorption.
The researchers discovered that coffee drinking correlated with an increase in several bacterial species, but the correlation with L. asaccharolyticus growth was by far the strongest, even with decaffeinated coffee.
Thai
Elite Member
And above study may explain this??
Coffee Consumption and the Risk of Colorectal Cancer - PMC
“Coffee consumption may be inversely associated with risk of CRC in a dose-response manner.”
Coffee Consumption and the Risk of Colorectal Cancer - PMC
“Coffee consumption may be inversely associated with risk of CRC in a dose-response manner.”
Thai
Elite Member
Just a moment...
Question: Does consumption of caffeinated coffee have a beneficial, detrimental, or neutral effect on the risk of recurrent atrial fibrillation (AF) episodes?
Findings: In this multicenter randomized clinical trial including 200 patients with persistent AF undergoing cardioversion, the risk of recurrent AF was significantly lower in the group allocated to coffee consumption (47%) compared with the abstinence group (64%).
Meaning: Consumption of coffee and other caffeinated products may be reasonably considered in patients with AF.
Question: Does consumption of caffeinated coffee have a beneficial, detrimental, or neutral effect on the risk of recurrent atrial fibrillation (AF) episodes?
Findings: In this multicenter randomized clinical trial including 200 patients with persistent AF undergoing cardioversion, the risk of recurrent AF was significantly lower in the group allocated to coffee consumption (47%) compared with the abstinence group (64%).
Meaning: Consumption of coffee and other caffeinated products may be reasonably considered in patients with AF.
Phoenix4Runner77
New member
This is interesting, I wonder why coffee consumption is associated with a benefit?
Thai
Elite Member
Coffee has anti-inflammatory and anti-oxidant properties. It is pretty magical.
I drink black caffeinated large cup everyday.
