Not trying to beat this topic to death, :deadhorse:BUT I recently changed plugs in our three 4runners without anti-seize, but I find it interesting that NGK says to bottom out the plug by hand and then go about another 2/3 of a turn.
The box ALSO says to torque the plug 18 ft lbs if you have a torque wrench.
The FSM says 13 ft lbs and makes no mention of anti-seize.
What I noticed is that 13 ft lbs is more than 2/3 of a turn so 18 ft lbs has to be even more than that.
At any rate, I don't use anti-seize and torque to 13 ft lbs wit YMMV