MechMike10,
I have driven the Trans-Lab highway twice, the second time a year ago this past summer. I was pulling a 24 foot trailer both times, the first with a '99 Land Cruiser and this last time with an '04 Tundra. Huge sections of this road have been upgraded between our first and second trips. Seriously, you do not need ten ply tires to run this road. The Cruiser had Michelins on it and I ran 40 PSI, if I remember correctly. I had BFGs on the Tundra last year. No tire problems on either trip, which totaled about 15,000 miles each. The highway is a combination of gravel and paved. Where is it gravel, the dust can be horrific. I just sloe3d down to 20 MPH or so till it cleared. There are LARGE trucks that travel that road and they do not slow down very much when approaching, and like to drive in the middle of the road. Once you hit the Labrador border, the road is almost all paved to Goose Bay and is an easy 50-55 MPH road with a trailer. Stop at the Churchill Falls and walk the approximately 1 mile trail to where The Churchill Falls used to be. It's impressive. Stop in Churchill Falls, the town, and go on the tour they do of the hydro-electric plant that is there. You go down an elevator something like 900 feet below ground to the power station. From Goose Bay, the road is almost entirely gravel, but when we were on it, there was relatively little traffic. For a real treat, if you are there early in the season, take the side road to Saint Lewis. We spend three days there because there were HUGE icebergs floating in the bay. Also, I would advise taking a 5 gallon can of gas between Goose Bay and Red Bay. There are no gas stations between Goose Bay and Port Hope Simpson and it is about 260 miles, unless you go off the road to Cartwright, which involves a ninety mile each was trip. Have a great trip!! But, in my opinion, to answer your question, as long as your tires are good and you have a good spare for the trailer, as well as your truck, you should be OK. Cell service is essentially non-existent along almost all of the Trans-Lab