I am not sure what year your 4runner is. The 06+ have slightly wider fender flares than the 03-05 yrs. Mine is an 06 and the factory sport wheels have a +30mm offset, with my Spidertrax they are effectively -1.75mm and at that offset with the 265 width tires , they are still just slightly under flush. To stick out .75" to 1.25" past the fender will need some really wide tires and wheels with a large negative offset. From what I have read they would probably rub like crazy and need major timming. I have seen some pics with guys that have 305's that look like they are sticking out like you would like. Take a look through the lift and tire thread.