I found that if there was any metal near the unit, the GPS would not acquire satellites. I have to infer from this, that it would not be optimal to mount the head unit anywhere near metal or electronics, but have seen them mounted near the headliner or on the dash and apparently they work alright. I prefer to keep mine on a window mount over the dash, with a very minimalistic mount connection, and the satellite acquisition is very solid and very quick every time.
All of this being said, the FTM-400XDR apparently comes with an upgraded GPS module that may be much better at acquiring satellites in less than optimal locations within the vehicle.
As for mounting in the sunglass holder, unless you cut the plastic off the bottom, controlling the radio would be a PITA, since the two bottom knobs would be blocked. You can do a lot from the remote mic, but I still prefer to use the knobs for everything.