Hope the OP doesn't mind if I piggyback on this somewhat recent thread.
Just found out I'll be in Denver in September for a meeting. I'm planning to tack on a few extra days to fill out the weekend and drive around with the wife.
After a quick look at the map, the suggestions above and surfing some ideas on the net, here's my 2-1/2 day quick drive plan:
Start in Denver
285/126/67 south to Garden of the Gods and Pikes Peak (stay in Colorado Springs)
24/82 west to Maroon Bells, Aspen & Glenwood Springs to catch I70 east (stay in Vail)
I70 east to 40/34 north through Rock Mtn NP, 7/72 & 119S to Golden (or 119E to Boulder)
End back in Denver
Plenty of stops for hikes and pics.
Open to any other suggestions such as places I've missed, places to avoid, problems with this route, most importantly good places to eat (good bar in Denver?) Unfortunately we can't get too far south and west in the limited time.
Looking forward to seeing the mountains up close. Thanks in advance.
IMO that's a pretty ambitious trip, especially day two. And day three. It takes much longer to drive those routes than you would expect, partially due to the mountain roads, partially due to the oh wow stops you'll make everywhere. I think you'd spend 70% of your time driving.
If you do want to do this I'd suggest something simpler like head west and do mt Evans, should see mountain goats. Then head over to the best western in Frisco, vail (expensive) or if you have time Leadville.
Next day get up early and explore the mining area at Leadville briefly then head south then west by twin lakes, over independence pass and to maroon belles south of aspen (aspen==expensive) then over to glenwood springs and stay there. Last time we were there we went from Frisco to Maroon Belles to Glenwood Springs to Frisco. We didn't stop all that long at any one place but it was an all day trip.
Last day follow 70 and stop at hanging lake if you want a strenuous trail to a cool lake. Stop in Vail if you want, or go over to Breckenridge if you want or explore some areas west of Denver.
A better idea would be to just head up to Estes Park and get a place there, check reviews. There are some cottages on the river on the east edge of town. They are cheap, clean but nothing fancy and they have a gas grill on the deck over the river. Visit the Stanley hotel (shining movie) then head into RMNP and explore the east side. Before dusk head into the park and see how many elk you can count, be careful driving even in the western part of Estes Park.
Second day drive over the pass and get ice cream, theres supposed to be some great place in grand lake. The west side of the park is much different than the east.
Third day figure out what you want to do or see and head out. There are awesome trails some easy some harder, but great. I could give you a few to check out.