Thing is that physics doesn't work that way. There is a certain amount of leverage created by a wheel moved out from stock and it doesn't matter if it's through a 1.5" adapter or 1.5" of backspacing. The hub isn't going to know the difference and it does have greater leverage than an OEM setup. It will cause premature bearing failure but the degree to which it fails will be determined by how the vehicle is driven. A street driven vehicle may very likely get into the typical failure range but something that sees heavy off-road use will wear much sooner.
Additionally, both designs place the same stress on the studs because aftermarket wheels rarely use the OEM shank-style lugnuts, and instead use a tapered seat exactly like the adapters. Instead of simply holding the wheel flat to the hub and using the shank to control the rotational force, the lugnuts are now trying to control the rotational force of the wheel which pushes outward against the lugnuts and away from the hub - something a stock Toyota setup doesn't do.
This is why Toyota studs are weaker but again this is the case with both spacers and aftermarket wheels. The Toyota design is that the studs don't bear as much of a load as other companies because there is no tapered seat and they only have to control stresses on a single axis. Therefore, they don't need to be as beefy a stud and can run an M12 vs the 1/2" or M14 typically found on other trucks.
Where Spidertrax inner nuts sit along the OEM studs is the same as most aftermarket wheels I've seen which means similar stress on the OEM studs. It does offer an additional point of failure but given that the Spidertrax studs are much tougher than OEM, aside from the Spidertrax unit itself failing, it's not going to make any difference to a similarly backspaced wheel.
The lightness of the wheel also has nothing to do with this because it's the weight of the vehicle coming down that causes the force on the hubs and studs.