I've had several Toyotas, still own 3. Never had an issue with stock diffs unless they were beat on daily.
My supra had 420 at the wheels, beat on it quite a bit, diff is still fine with no problems.
My truck has seen lots of work, from rock trails to cruising down the highway at 80+mph for hours at a time. Aside from the shop that did a re-gear improperly (yep, wrong shim sizes) and losing the ring gear a week after the re-gear, its still going strong in the back end, that includes a Detroit locker.
Most diffs fail because someone tried to do their own re-gear without paying attention to the shim sizes they needed. "Close enough" does not cut it for toyota diffs!
So, where is your information from that you can state with fact that "4 runners have rear end issues"? I'd like to see these facts you speak of.