"I had a customer's 04 Sienna with the exact same complaint with the bizarre vent air temp issue. After A LOT of research and investigation I determined the problem was low R134A charge in A/C system. To prove my diagnosis I just charged the A/C system, which was over half low, and almost immediately all vents started blowing very cold air, equally. The key to finding the solution was looking at the heater/evaporator box illustration in the shop repair manual. The center vents come from the SAME open location inside the heater/evaporator box so you would think they both would blow at the same temp. Apparently NOT on 04 Sienna! When the evaporator is starved of R134 only half of it will cool, I know it's weird, but, half of the center vent blows cool, the other half blows warm ambient temp air. As far as I know this very strange problem only occurs on the 04 Sienna, but other years could also exhibit the same symptoms. I have been working on Toyotas for over 30 years and owned an Asian specialty repair shop for 25 years and this is one of the weirder problems I have encountered during my career. Hopefully if you have the same problem in your Sienna this information may help you obtain a relatively low cost fix. Cheers!"