Having re-geared to 4.56. It's a compromise between off road and mileage, especially running 285's duratracs.
I still get about 270ish all freeway and drops to 210ish mixed city/freeway and trail I don't even count I just bring 2 full rotopax now (extra 8ish gals)
I figured the superchargers power would compensate for 4:30 gears so that was off the table.
Just remember my supercharger was a gen 2 trd unit, and honestly it did not run perfect until I upgraded the fuel with 7th injector and controlled by urd's black box. Gadget is the man and sent a pretty good fuel map initially but I still needed dyno time to dial it in, to the specific parts I had installed, type of fuel (yeah Cali blend), and driving style. So that might factor in with extra cost, it's just not slap in the supercharger and everything is good to go.
Also i have an 02 runner and I actually had to replace my transmission with IPT unit and yes all their upgrades. My oem unit planetary gear exploded like a grenade, yes the planetary gear exploded (the shop was nice enough to show me the carnage). Not sure if the extra torque from the supercharger had an effect, my driving style on trails or a combination of both had its effect, also my girl is a heavy pig, triple locked, full armored, and sometimes a rtt.
Hope that helps.